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EDITED BY PROFESSOR YASSER METWALLY

March 2010

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Age dependant epileptic syndromes [Part I]

The age of the patients has great influence on the ictal, clinical and EEG characteristics of the epileptic seizures disorders and it also determines the course and prognosis of epilepsy in general. This is particularly true in the first two decades of life, especially for infancy and early childhood. There are certain age- determined epileptological entities or epileptic conditions which appear to be monolithic, in spite of a wide variety of etiologies and probably also despite variations in the localization of cerebral involvement. The role of age in epileptic seizure disorder has been substantiated by experimental work and clinical electroencephalographic investigations. We find in age-determined epileptic conditions a) certain condition-related types of seizures, b) certain condition-related EEG patterns, and c) certain condition-related characteristics of course and prognosis..Click here for the whole story

Neonatal convulsions

In the neonatal period of life, epileptic seizures are fairly common and may be caused by a wide variety of etiologies. There is some reason to presume that neonatal convulsions play a greater role in the lives of full-term infants than in premature infants, notwithstanding the high risk of brain damage caused by prematurity. The neonatal period may be extended to the first 3 mos of life by some, while holders of a stricter view limit this period to the first 3 wk. Neonatal convulsions are common; their prevalence may range from 0.2% to 1.2% of all live births. Click here for the whole story

Infantile spasms (hypsarrhythmia)

Infantile spasms consist of sudden tonic and myoclonic phenomena. The term "infantile spasms" is quite satisfactory from the clinical viewpoint and should be preserved. "Hypsarrhythmia" is an EEG term which denotes the EEG correlate of the condition and has found surprisingly wide acceptance with clinicians; a clinical term such as infantile spasms is certainly preferable as far as the clinical condition as such is concerned. .Click here for the whole story

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